RT Journal A1 Goodwin DW T1 PSychiatry and the mysterious medical complaint JF JAMA JO JAMA YR 1969 FD September 22 VO 209 IS 12 SP 1884 OP 1888 DO 10.1001/jama.1969.03160250040009 UL http://dx.doi.org/10.1001/jama.1969.03160250040009 AB When patients complain of pain or some other physical symptom, and no physical cause can be found, it is not enough to suggest that the symptom is functional or psychological. The physician should rule out three psychiatric disorders in which unexplained physical symptoms often dominate the clinical picture. These are hysteria, anxiety neurosis, and depression. Each is a definite syndrome with specific diagnostic criteria and a well-documented natural history. Hysteria and anxiety neurosis often can be managed as successfully by an internist or general practitioner as by a psychiatrist. Depression more often justifies a psychiatric referral. "Functional" symptoms which cannot be attributed to one of these syndromes often warrant further search for an organic cause.