RT Journal
A1 Kalivas J
T1 A guide to the problem of photosensitivity
JF JAMA
JO JAMA
YR 1969
FD September 15
VO 209
IS 11
SP 1706
OP 1709
DO 10.1001/jama.1969.03160240062018
UL http://dx.doi.org/10.1001/jama.1969.03160240062018
AB Cutaneous eruptions more or less confined to light-exposed areas are not uncommon. Despite numerous exhaustive reviews1-7 published in recent years, it is difficult for most practitioners to acquire a real diagnostic expertise in this field. Too often, the only characteristic feature in any given case is the distribution of the lesions. Hopefully, the following schemes will provide some new perspectives and helpful insights by plotting differentiating features as attributes against the primary light-sensitive dermatoses; by commenting on the more important (or more interesting) photosensitizing drugs and contactants; and, finally, by indicating which laboratory tests are likely to be of specific diagnostic value when the history and physical findings are inconclusive (as, for example, in protoporphyria).I. The physical examination and historyB. Extrinsic photosensitivity1. Internal agents* (drug-induced)Sulfonamides†—uncommon with modern analogues, in contrast to the older drug, sulfanilamideSulfonylureas†Thiazides,† quinethazone†—may have only pruritus in sun-exposed sites