RT Journal
A1 Friedman S
T1 PSychopharmacology
JF JAMA
JO JAMA
YR 1969
FD July 28
VO 209
IS 4
SP 565
OP 565
DO 10.1001/jama.1969.03160170061031
UL http://dx.doi.org/10.1001/jama.1969.03160170061031
AB In a scant 15 years psychopharmacology has come of age; this book confers upon it the mantle of maturity. A welcome relief from psychiatric cant and theory, it summarizes in magnificent scope our scientific knowledge of drugs currently available in psychiatric therapeutics. In some 450 double-columned pages, the history, chemical composition, physiological-pharmacological action, and clinical investigation of every pertinent drug have been superbly reviewed.In certain areas the experience of individual investigators may differ somewhat from some opinions expressed in this extensive presentation. For example, I have not found that the desmethylated compounds of imipramine or amitriptyline act more rapidly than their parent drugs. Nor have I been able definitely to correlate the ultimate response to the antidepressant drugs with their therapeutic action during the first week of administration, since their effect during that early period is usually quite negligible. My experience negates the use of these compounds in personality