RT Journal
A1 Schwarz G
T1 COnstrictive pericarditis and irradiation therapy
JF JAMA
JO JAMA
YR 1969
FD July 28
VO 209
IS 4
SP 561
OP 561
DO 10.1001/jama.1969.03160170057020
UL http://dx.doi.org/10.1001/jama.1969.03160170057020
AB To the Editor:— 
    In "Constrictive Pericarditis Following Irradiation Therapy" (207:2281, 1969), Cathel E. Macleod, et al rule out the possibility that pericardial fibrosis might be the result of stromal reaction to malignant cell implantation on the basis of autopsy findings which failed to reveal any malignant cells in the treated areas. With a tumor dose of 4,600 rads to the pericardium, the probability of encountering a surviving seminoma cell is practically nil, and the absence of these cells only proves that irradiation was effective in eradicating them. This, however, does not affect the validity of the other findings in this case which were of great interest and which emphasizes that mediastinal irradiation must be given expertly and judiciously.