RT Journal
T1 MEdical news
JF JAMA
JO JAMA
YR 1969
FD July 7
VO 209
IS 1
SP 17
OP 30
DO 10.1001/jama.1969.03160140007003
UL http://dx.doi.org/10.1001/jama.1969.03160140007003
AB Soluble, Buffered Aspirin Sought To Eliminate Blood Loss In Stomach 
    Work on a type of buffered, soluble aspirin intended to eliminate stomach bleeding—a little known side effect of the widely used drug—is nearing completion, a Cleveland investigator told the American Rheumatism Association meeting in Boston."Evidence is accumulating in a number of laboratories that we have not been using aspirin correctly all these years by taking tablets," said Jack R. Leonards, MD, PhD, associate professor of biochemistry at Case Western Reserve University School of Medicine."Hopefully, the aspirin of the future will be a tablet you drop into a glass of water and take after it dissolves."The drug would be used initially by persons suffering from rheumatoid arthritis.Conventional aspirin is not easily soluble in cold water. The result is that tablets break up into small particles after they arrive in the stomach. These particles lodge on the stomach