RT Journal
A1 Haynes RE, Cramblett HG, Kronfol HJ
T1 EChovirus 9 meningoencephalitis in infants and children
JF JAMA
JO JAMA
YR 1969
FD June 2
VO 208
IS 9
SP 1657
OP 1660
DO 10.1001/jama.1969.03160090017004
UL http://dx.doi.org/10.1001/jama.1969.03160090017004
AB Echovirus 9 meningoencephalitis in 196 children was confirmed by the isolation of the virus from the cerebrospinal fluid of each patient. Although the illness was usually mild, one patient died. The cerebrospinal fluid (CSF) leukocyte counts were unusually high in some patients, and CSF protein content was over 100 mg/100 cc in nine patients. The glucose content of all specimens of cerebrospinal fluid was normal. Echovirus 9 was recovered from 57% of the CSF specimens of patients with a clinical diagnosis of aseptic meningoencephalitis who were studied between May 19, 1968, and Sept 30, 1968. In patients who had specimens from multiple sites available for culture, 76 yielded echovirus 9 from one or more sites, and of these 76 patients, 66 (87%) had virus recovered from a CSF specimen.