RT Journal A1 Ratnoff OD T1 CLinical interpretation of laboratory tests JF JAMA JO JAMA YR 1969 FD April 21 VO 208 IS 3 SP 537 OP 537 DO 10.1001/jama.1969.03160030111028 UL http://dx.doi.org/10.1001/jama.1969.03160030111028 AB In teaching clinical medicine, all of us are accustomed to moralize to our students that the good physician makes a diagnosis by listening to the patient's story and then examining him. The laboratory, we tell them, is a crutch with which we affirm our bedside impression. Of course, whatever the didactic value of such dogma, it is in essence a call for a return to that simpler life when we lived in a rural society and a good glass of beer cost a nickel. In reality, diagnosis can be based only upon objective evidence; all else is surmise. Whatever the history or physical examination reveals, it is study of the peripheral blood smear and bone marrow that affirms that the patient has chronic myeloid leukemia. Our clinical impressions tell us what to look for, but the laboratory tells us what we have found. When we are still without adequate laboratory