RT Journal
A1 Rodriguez M, Paronetto F, Schaffner F, Popper H
T1 ANtimitochondrial antibodies in jaundice following drug administration
JF JAMA
JO JAMA
YR 1969
FD April 7
VO 208
IS 1
SP 148
OP 150
DO 10.1001/jama.1969.03160010144026
UL http://dx.doi.org/10.1001/jama.1969.03160010144026
AB Antimitochondrial antibodies were detected by fluorescent antibody technique in seven of nine sera from patients with jaundice after halothane anesthesia, and from four of seven patients with jaundice after therapy chlorpromazine. They were not observed in jaundized patients treated with other drugs (methyldopa, aminosalicylic acid, chlorpropamide, perphenazine), in patients in whom jaundice did not develop after receiving halothane or chlorpromazine, or in patients with viral hepatitis. The presence of antibodies may help differentiate between viral hepatitis and some forms of jaundice after drug administration.