RT Journal T1 MAlignant brain tumor JF JAMA JO JAMA YR 1969 FD February 24 VO 207 IS 8 SP 1510 OP 1510 DO 10.1001/jama.1969.03150210094014 UL http://dx.doi.org/10.1001/jama.1969.03150210094014 AB The outlook for the patient with a brain tumor has improved dramatically in the past decade. This is the result of many factors, including the ability of the profession generally to recognize brain tumors much earlier, and the greatly increased accuracy in diagnostic procedures and much improved treatment. The surgical mortality with malignant gliomas (glioblastoma multiforme) of the brain in the decade 1944 to 1954 was almost 50%; at present it is less than 3%.1 But merely to survive an operation for removal of a brain tumor is not enough. Life must be prolonged, and the condition of the patient must be such that he can enjoy the additional years granted him, and can work and support himself and his family.In the past the outlook with glioblastoma multiforme of the brain has been so poor that most neurologists and many neurosurgeons advocated that no effort be made to