RT Journal T1 CUrrent comment JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1949 FD August 13 VO 140 IS 15 SP 1220 OP 1220 DO 10.1001/jama.1949.02900500028012 UL http://dx.doi.org/10.1001/jama.1949.02900500028012 AB NODULAR PANNICULITIS—WEBER-CHRISTIAN DISEASE  Weber-Christian's disease, or nonsuppurative nodular panniculitis, is characterized by recurring episodes of fever and the development of numerous painful and slightly tender subcutaneous nodules. In only 3 of 33 recorded cases was death apparently due to the disease. In the case reported by Kritzler,1 in which necropsy was done, the nodular lesions were limited to the subcutaneous fat. However, fat emboli were found in the lungs and there was widespread acute necrosis of the liver and spleen. In the case examined at necropsy by Spain and Foley,2 necrotic areas were found not only in the subcutaneous fat but in the mesenteric, omental and pretracheal fat. Fat emboli were not found in the lungs, nor were areas of necrosis observed in the liver or spleen. However, foci of fat necrosis were present in the region of the pancreas. A third case investigated at necropsy was that