RT Journal
A1 Toomey JA
T1 NEurologic complications following administration of pertussis vaccine-reply
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1949
FD June 11
VO 140
IS 6
SP 556
OP 556
DO 10.1001/jama.1949.02900410051020
UL http://dx.doi.org/10.1001/jama.1949.02900410051020
AB To the Editor:— 
    I have read Dr. Matthew Brody's manuscript. I was unfamiliar with the Brooklyn Hospital Journal report of April 1947.As Brody states, his patient may have had undiagnosed pertussis, the patient producing his own antigen with the disease. This could institute an antigen-antibody reaction.Patient 2 had, a reaction following the second injection cf pertussis vaccine, a clear-cut antigen-antibody phenomenon.The third case is not clear—it was in a person with a neurologic disease who had a trigger type of response. There was a long incubation period of five weeks in a patient with kernicterus encephalopathy which followed the usual pattern. This might have been the etiologic factor.I am glad to note that the author agrees that a second injection of pertussis vaccine should be cautiously given to anyone who has had a previous reaction, that injection should not be made in a person with a