RT Journal T1 A female alexis st. martin JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1949 FD June 11 VO 140 IS 6 SP 540 OP 540 DO 10.1001/jama.1949.02900410036009 UL http://dx.doi.org/10.1001/jama.1949.02900410036009 AB When William Beaumont treated Alexis St. Martin, whose stomach as a result of a shotgun wound could be viewed directly through an external opening, he made physiologic observations which greatly increased our knowledge of the physiology of the stomach. These studies were carefully made for many years and have become a classic example of research limited largely to simple and direct clinical investigation.Since these pioneer studies, other observers have gained insight regarding gastric physiology by observing other persons who have, for one reason on another, presented external openings through which the interiors of their stomachs could be examined. Until recently all these patients were male. Now a woman patient with a large gastric fistula has become available for study and observations have been made which in some respects at least differ from those made in the male.These recent observations were made on a Negro woman, 24 years old,