RT Journal A1 RANDALL CL T1 MAnagement of complications of endometriosis JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1949 FD April 9 VO 139 IS 15 SP 972 OP 976 DO 10.1001/jama.1949.02900320002002 UL http://dx.doi.org/10.1001/jama.1949.02900320002002 AB Women experience varied discomforts due to endometriosis. It must first be decided which to consider complications of the disease. The site of an endometrioma does not of itself assure development of difficulties, and extragenital or extrapelvic foci may not cause eventual distress. Often there seems little correlation between the severity of symptoms and the extent of the disease. Certainly, for the purposes of this discussion, unexpected or undesirable effects of endocrine, radiation or surgical treatment should not be ascribed to endometriosis. I would consider as complications disturbances resulting whenever disseminated superficial lesions or a single penetrating nodule, symptomatically or mechanically, interferes with the function of the reproductive, urinary or digestive tracts.Such complications give rise to nonspecific symptoms, all of which are commonly due to lesions other than endometriosis. The mere fact that a patient's complaints may be due to this disease tends to keep attention focused on this possibility.