RT Journal A1 Scott J T1 ANtabus® for alcoholism JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1949 FD April 2 VO 139 IS 14 SP 954 OP 954 DO 10.1001/jama.1949.02900310058022 UL http://dx.doi.org/10.1001/jama.1949.02900310058022 AB To the Editor:—  As you know, a new approach to the medical management of alcoholism was recently reported in the Scandinavian as well as the British literature (Acta pharmacol. et toxicol. 4:285-321 [Dec.] 1948; Lancet2: 1001 [Dec. 25] 1948). The substance used was antabus,® a highly purified brand of tetraethylthiuramdisulfide specially prepared by Medicinalco, Copenhagen, Denmark. Antabus® is capable of producing pronounced physical discomfort when it is taken prior to the ingestion of alcohol and tends to create in the alcoholic patient a disinclination to drink. On this basis, its value as an adjunct to recognized psychotherapeutic measures has been suggested (Lancet2: 1004 [Dec. 25] 1948).Because of the sociologic significance of this development, widespread interest has been aroused by the publicity which antabus® has received in the United States. This letter is sent to you with the thought that it may provide a means of informing