RT Journal
T1 PRovisional definition of poliomyelitis virus
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1949
FD March 26
VO 139
IS 13
SP 852
OP 852
DO 10.1001/jama.1949.02900300038014
UL http://dx.doi.org/10.1001/jama.1949.02900300038014
AB Confusion regarding restrictions that should be applied to the term poliomyelitis virus, as opposed to other allied terms such as encephalomyelitis or encephalitis virus, has recently been considered by the Committee on Nomenclature of the National Foundation for Infantile Paralysis. Recommendations submitted were that the term poliomyelitis virus be used only to designate strains of the agent originally described as the cause of poliomyelitis in man, regardless of the source from which it may be recovered in nature. The identifying characteristics of this virus are the production of typical experimental disease in the monkey, the characteristics and distribution of histologic lesions in the spinal cord and brain of primates, the host range of the virus and its immunologic properties.The clinical signs of disease in monkeys include fever, tremor and spasticity of muscles, usually followed by paralysis within a day or two. Severe generalized tremors are considered almost without exception