RT Journal T1 CUrrent comment JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1939 FD June 10 VO 112 IS 23 SP 2424 OP 2424 DO 10.1001/jama.1939.02800230048019 UL http://dx.doi.org/10.1001/jama.1939.02800230048019 AB STUDIES ON RHEUMATIC FEVERĀ  Recent studies on rheumatic fever by Schultz and Rose1 have yielded facts with suggestive diagnostic implications. Determination of the glutathione content of erythrocytes and of the catalytic potency of the blood in rheumatic fever as well as an investigation of the dextrose tolerance curves of persons with this disease did not yield particularly striking results. An investigation of the novel formol-gel reaction of Gate and Papacostas2 in a number of febrile diseases with particular reference to rheumatic fever, however, led to interesting observations. In patients with various febrile diseases it was found that, in general, a parallel was demonstrable between the erythrocyte sedimentation rate and the results of the formol-gel reaction, the incidence of positive gel reactions varying directly with acceleration of the sedimentation rate. In patients with rheumatic carditis, however, negative formol-gel reactions were often observed early in the disease, although at the