RT Journal
A1 Paterson JC
T1 "Relation of physical exertion and emotion to precipitation of coronary thrombi"
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1939
FD June 3
VO 112
IS 22
SP 2346
OP 2346
DO 10.1001/jama.1939.02800220112024
UL http://dx.doi.org/10.1001/jama.1939.02800220112024
AB To the Editor:— 
    A communication by Drs. Masters, Dack and Jaffe in The Journal April 22 referring to my paper entitled "Relation of Physical Exertion and Emotion to Precipitation of Coronary Thrombi" in The Journal March 11 deserves some comment.I am afraid that your correspondents have missed the main point in my paper. I have shown that the formation of coronary thrombi is gradual, sometimes occupying several days before occlusion with its resulting precordial pain is produced. The onset of precordial pain, then, merely marks the final phase of a process which was initiated (by capillary rupture) some time previously. Therefore the activities of a patient just before the onset of precordial pain, as tabulated in 1,400 cases by your correspondents, are purely coincidental and have no relation to the cause of thrombus precipitation. Their smaller series of 250 cases warrants more attention. I have the greatest respect for