RT Journal
A1 Goldblatt H
T1 EXperimental renal atrophy
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1939
FD May 27
VO 112
IS 21
SP 2190
OP 2191
DO 10.1001/jama.1939.02800210084026
UL http://dx.doi.org/10.1001/jama.1939.02800210084026
AB To the Editor:— 
    In an editorial (The Journal, April 8, p. 1344) on the recent work of Drury (J. Exper. Med.68:693 [Nov.] 1938) entitled "Experimental Renal Atrophy," which deals with experimental renal insufficiency and hypertension in the rabbit, several statements are made which are misleading. The writer of the editorial states that the application of our clamp (Goldblatt, Harry; Lynch, James; Hanzal, R. F., and Summerville, W. W.: J. Exper. Med.59:347 [March] 1934) to the main renal artery, like other technics employed for the purpose of producing experimental hypertension, produces necrosis or other pathologic changes in the kidney tissue, particularly in rabbits. Although it is true that necrosis can be produced at will by our method by excessive constriction of the main renal arteries and that this is more likely to occur in small animals, yet it is equally true, and of the greatest importance, that