RT Journal A1 Luckhardt AB T1 INvestigations on antibodies JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1939 FD March 25 VO 112 IS 12 SP 1181 OP 1182 DO 10.1001/jama.1939.02800120067025 UL http://dx.doi.org/10.1001/jama.1939.02800120067025 AB To the Editor:—  What does the writer of the editorial mean when he says in "Recent Investigations on Antibodies" (The Journal, February 25, p. 735): "The investigators, however, have for the first time applied quantitative immunochemical technics to the problem of splenic immunity." Does he not consider the technics of Hektoen and Carlson quantitative or my work, using such methods, qualitative? Has he seen my "A Study of the Origin of the Immune Bodies by the Method of Organ Transplantation" (Proc. Soc. Exper. Biol. & Med.7:122-124, 1910)? Or, more to the point, because more physiologic, has the writer of the editorial read the work (confirmed later by Preston Kyes using intermediate dilutions) entitled "The Relation of the Spleen to the Fixation of Antigens and the Production of Immune Bodies" by Luckhardt and Becht, Am. J. Physiol.28:257-274 [Aug. 1] 1911)?In these papers the spleen is shown