RT Journal A1 Brussel JA T1 COngenital absence of bones of the lower limb JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1939 FD March 18 VO 112 IS 11 SP 1050 OP 1052 DO 10.1001/jama.1939.62800110002007a UL http://dx.doi.org/10.1001/jama.1939.62800110002007a AB While anomalous conditions, present at birth, of the bones of the leg and foreleg are not rare, they are sufficiently unusual to be reported and should be recorded to maintain accurate statistics in these cases. Unfortunately, the figures of the early eras, particularly those prior to use of the roentgenogram, have been inaccurate chiefly because of the paucity of clinical means to ascertain definite pathologic conditions and, as a result, some of these observations have since been revised. For example, in 1846 Proudfoot (quoted by Cotton and Chute) reported a case of congenital absence of the fibula in which he stated that "... the tibia of the same limb seemed to have a compound fracture at the middle...."Freund1 regards the figures of Nilsonne2 as the most conservative in the review of congenital absence of the femur. The latter collected seventy-two cases up to 1928 and added ten of