RT Journal
A1 Bigler JA
T1 LOss of subcutaneous fat of the lower extremities (lipodystrophy)
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1939
FD February 18
VO 112
IS 7
SP 627
OP 628
DO 10.1001/jama.1939.62800070001010
UL http://dx.doi.org/10.1001/jama.1939.62800070001010
AB Lipodystrophy is a disorder in which there is a loss of subcutaneous fat. The loss is absolute in that in the affected areas there is a complete absence of the subcutaneous tissue fat. None of the other tissues seem to be involved. The face is affected most commonly and more markedly than other parts of the body. The absence of fat is not congenital, because in affected persons the fat has previously been present in the regions from which it disappears. In some reported cases there has been an apparent increase in the fat of the lower part of the body. The condition is undoubtedly a disease entity rather than a symptom complex because of the absence of any other clinical, physical or pathologic manifestations. In association with other diseases there may be a marked decrease in the amount of subcutaneous fat but the fat loss is never absolute. The