RT Journal
A1 EMMETT J
T1 REfractory amebic abscess of the liver treated with chloroquine
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1949
FD September 3
VO 141
IS 1
SP 22
OP 24
DO 10.1001/jama.1949.62910010002005a
UL http://dx.doi.org/10.1001/jama.1949.62910010002005a
AB In 1948 Conan1 reported 6 cases of hepatic amebiasis (without abscess of the liver) successfully treated with chloroquine. In the same year Murgatroyd and Kent2 reported the cure of a case of refractory amebic abscess of the liver treated with chloroquine. The success of this treatment, after the failure of emetine, diiodo-hydroxyquinoline (diodoquine®) and penicillin given systemically and proflavine sulfate used locally, was striking. In 1949 Conan confirmed the efficacy of chloroquine against hepatic amebiasis (without abscess) with the report of several more cases in which it was used with success.3The purpose of this article is to report a second case of refractory amebic abscess of the liver, which has been successfully treated by chloroquine, confirming the result reported by Murgatroyd and Kent.REPORT OF CASE 
    H. S., a white man aged 53, was admitted on Feb. 1, 1949 after transfer from another institution, where he had