RT Journal A1 Potts WJ T1 CArotinemia in an adult JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1929 FD July 6 VO 93 IS 1 SP 30 OP 31 DO 10.1001/jama.1929.27110010002008a UL http://dx.doi.org/10.1001/jama.1929.27110010002008a AB Carotinemia as a clinical entity was established by the work of Hess and Meyers1 in 1923. They observed a peculiar symptomless discoloration of the cheeks, alae nasi and forehead, and occasionally a generalized tinting of the skin in children fed on a high carrot diet. They were able to produce the pigmentation by the administration of carotin, and they saw it disappear when the pigment was withheld and the pigment-bearing vegetables were eliminated from the diet. It was also discovered that spinach, oranges and egg yolk contain a large amount of carotin.DeBuys2 reported two interesting cases of carotinemia in new-born children, observed and studied in 1911 and 1913, and diagnosed in 1923 after the publication of the paper by Hess and Meyers. A high vegetable diet had been advised for the mother, who took the advice too literally and practically lived on green vegetables. Each child when