RT Journal
A1 Bromberg L, Murphy P
T1 AGranulocytic angina following prophylactic typhoid vaccination
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1929
FD April 13
VO 92
IS 15
SP 1266
OP 1267
DO 10.1001/jama.1929.92700410004011e
UL http://dx.doi.org/10.1001/jama.1929.92700410004011e
AB In a survey of the literature from the first description of agranulocytic angina by Schultz1 in 1922 up to December, 1928, we have found a total of 152 cases conforming in general to the clinical criteria that he outlined. Although the etiology of the disease is entirely unknown, most observers are agreed that the marked reduction or total absence of granular leukocytes, which is the remarkable finding common to all cases, occurs as a result of some obscure septic or toxic bone marrow depressant. We have recently observed a case showing abnormal reaction of the hematopoietic system which occurred so directly after prophylactic injections of typhoid vaccine as to suggest that this may have been the toxic agent that incited the clinical manifestations of agranulocytic angina. This is a circumstance previously unmentioned in the literature.REPORT OF CASE 
    E. W. L., a white woman, aged 50, entered the Jewish Hospital