RT Journal T1 EFfects of loss of gastric juice JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1929 FD March 2 VO 92 IS 9 SP 724 OP 725 DO 10.1001/jama.1929.02700350032013 UL http://dx.doi.org/10.1001/jama.1929.02700350032013 AB The profound significance of undue losses of water from the body has not been adequately appreciated until recent years. In reviewing the subject, Marriott5 has pointed out that the organism possesses an available store of water which exists for the greater part in the muscles and in the skin, and which can be drawn on to some extent before any considerable degree of desiccation of other parts of the body occurs. As larger amounts of water are withdrawn a drying out of all parts of the organism takes place, but the degree of desiccation varies markedly in the different organs. The withdrawal of fairly large amounts of water from the muscles (from 10 to 20 per cent of their total water) fails to impair their function, as determined by electromotor activity of the excised muscles, nor is there any apparent morphologic change. The skin also seems to be but