RT Journal
A1 SMITH JH
T1 INtra-abdominal inflammation in relation to diabetic acidosis with leukocytosis
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1929
FD January 26
VO 92
IS 4
SP 308
OP 309
DO 10.1001/jama.1929.02700300032008
UL http://dx.doi.org/10.1001/jama.1929.02700300032008
AB In severe diabetic acidosis an acute abdominal lesion may be closely simulated, and again such a lesion may actually exist. The diagnostic difficulty is increased by the claim that leukocytosis may occur in acidosis independent of the inflammatory factor. Doubtless every observer has hesitated to accept this conclusion, feeling that the acidosis may have been precipitated by an inflammatory state that was not recognized. This hesitation would be more strongly felt if a fair percentage of patients did, at one time or another, develop recognized and demonstrable abdominal disease, such as acute appendicitis. However, a number of careful observers have reported their conclusion that otherwise uncomplicated diabetic acidosis may be characterized by leukocytosis.1Some of the following abstracts of cases emphasize the importance of a guarded acceptance of acidosis as the cause of abdominal symptoms and leukocytosis, while others suggest the validity of the belief that both abdominal pain