RT Journal A1 Parker WG T1 "The relationship between herpes zoster, syphilis and chickenpox" JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1919 FD November 22 VO 73 IS 21 SP 1629 OP 1630 DO 10.1001/jama.1919.02610470065031 UL http://dx.doi.org/10.1001/jama.1919.02610470065031 AB To the Editor:  —I have read your editorial on the relationship between herpes zoster, syphilis and chickenpox. The segmental distribution and spinal findings indicate that it may have a central causative factor, as distinguished from peripheral nerve irritations. Some time ago I had a case of gallstone disease in which occurred a marked herpetic eruption over the abdomen in the region of the gallbladder. At this time the patient was suffering from repeated attacks of colic with marked jaundice, evidently due to common duct blockage. I operated on her a few days later, the jaundice having cleared up considerably, and at that time found the cystic duct obstructed by a large stone, as well as a number of stones in the gallbladder. I have no doubt that in this particular case there was so much irritation about the gallbladder neck that a "reflex irritation" brought about the external herpetic eruption