RT Journal
A1 SOLLMANN T
T1 THe solubility of intestinal ipecac preparations
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1919
FD October 11
VO 73
IS 15
SP 1125
OP 1127
DO 10.1001/jama.1919.02610410027008
UL http://dx.doi.org/10.1001/jama.1919.02610410027008
AB The reputed value of ipecac against intestinal amebas was originally based on its oral administration. Its nauseant and emetic actions, however, constituted serious drawbacks to its use. The coating of pills with salol is not always satisfactory, although, with due care, it appears to be quite feasible.1 The hypodermic injection of emetin hydrochlorid avoids the local actions; but used thus, it often fails to rid the patient of amebas, especially if he is a chronic carrier. Attempts have therefore been made to solve the problem by the use of emetin compounds that, while insoluble in the stomach, would be soluble in the intestine. The basis of these attempts lies in the difference between the reaction of the stomach and that of the intestine.EMETIN BISMUTH IODID 
    Emetin bismuth iodid is described in New and Nonofficial Remedies and a further description is found in the report of the Council on