RT Journal
T1 ELimination of the physiologic products of muscular work
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1919
FD September 27
VO 73
IS 13
SP 988
OP 989
DO 10.1001/jama.1919.02610390040016
UL http://dx.doi.org/10.1001/jama.1919.02610390040016
AB Although the physiology of exercise has long interested scientific investigators, its importance has become greatly augmented of late through the demand for greater personal efficiency and a larger industrial output. Fatigue sets a limit to work. Greater working capacity can be attained only through an understanding of the nature of fatigue, so that it can be decreased as far as possible. For many years it has been understood that muscular activity is attended with the production of substances of an acid nature. When they accumulate in the contractile tissues, the efficiency of the muscle is soon impaired; and the satisfactory continuance of muscular performance depends on the removal or the destruction of the acid "fatigue products."In view of this aspect of muscular activity, it is conceivable that hard work will result in the discharge of acid products into the circulation to an unusual degree. How are they disposed of?