RT Journal
T1 NAusea and vomiting of pregnancy
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1919
FD June 7
VO 72
IS 23
SP 1678
OP 1678
DO 10.1001/jama.1919.02610230032010
UL http://dx.doi.org/10.1001/jama.1919.02610230032010
AB A group of symptoms affecting the pregnant woman and varying in severity from mild "morning sickness," through a range of more intense nausea, to the extreme of "pernicious vomiting" presents difficulties that are not always easy to combat. The theories advanced in explanation of the origin of these phenomena are unsatisfactory because most of these theories bear on symptoms that are at best only part of the possibilities presented by this particular type of nausea and vomiting. Acidosis, for example, which has been one of the explanations offered in the past, fails to account for the features observed in many instances. The hypothesis of "suboxidation" has not justified itself in attempting to explain these, as well as various other, pathologic disturbances. The hypothetic poison has not been discovered. The alleged accumulation in the blood of nonmetabolized nitrogenous compounds, such as amino-acids, has not been substantiated. As recent writers have summarized