RT Journal A1 Vesper HW, Kuiper HC, Mirel LB, Johnson CL, Pirkle JL T1 LEvels of plasma trans-fatty acids in non-hispanic white adults in the united states in 2000 and 2009 JF JAMA JO JAMA YR 2012 FD February 8 VO 307 IS 6 SP 562 OP 563 DO 10.1001/jama.2012.112 UL http://dx.doi.org/10.1001/jama.2012.112 AB To the Editor : Levels of trans-fatty acids (TFAs) in blood come from natural sources, such as milk, and industrial sources, such as partially hydrogenated vegetable oils. Dietary intake of TFAs increases low-density lipoprotein cholesterol (LDL-C) and has other adverse metabolic effects.1 Changing to a diet low in TFAs may lower the LDL-C level and decrease the risk for cardiovascular disease. To assist consumers, the Food and Drug Administration amended its regulations in 2003 to require that TFA content be declared on the nutrition label of foods and dietary supplements.2 Some community and state health departments have required restaurants to limit TFAs and reductions have been shown in supermarket and restaurant products.