RT Journal
A1 Hanto DW
T1 A 50-year-old man with hepatitis c and cirrhosis needing liver transplantation
JF JAMA
JO JAMA
YR 2003
FD December 24
VO 290
IS 24
SP 3238
OP 3246
DO 10.1001/jama.290.24.3238
UL http://dx.doi.org/10.1001/jama.290.24.3238
AB 
During a routine life insurance evaluation in 1991, Mr G was found to
have abnormal liver function test results and was diagnosed with non-A, non-B
hepatitis. Liver biopsy showed mild periportal inflammation. In 1995, he was
found to have antibodies to hepatitis C. He was treated with interferon and
ribavirin but did not improve. A liver biopsy in 2001 revealed grade II to
III inflammation, stage IV fibrosis. He was subsequently treated with pegylated
interferon and ribavirin and again did not improve. In 2001, he developed
transient ascites and encephalopathy, with unsteady gait and forgetfulness.
In 2002, Mr G bled from esophageal varices and underwent a transjugular intrahepatic
portosystemic shunt (TIPS) procedure, requiring revision 1 week later. Since
that time, he has been on the liver transplant waiting list.