RT Journal A1 Kottke TE, Stroebel RJ, Hoffman RS T1 JNc 7—it's more than high blood pressure JF JAMA JO JAMA YR 2003 FD May 21 VO 289 IS 19 SP 2573 OP 2575 DO 10.1001/jama.289.19.2573 UL http://dx.doi.org/10.1001/jama.289.19.2573 AB The World Health Organization has estimated that high blood pressure causes 1 in every 8 deaths worldwide, making hypertension the third leading killer in the world.1 The JNC 7 report,2 published in this issue of THE JOURNAL, summarizes how the burden of hypertension can be decreased. Among the messages emphasized is that systolic blood pressure control should be the focus of treatment. Cardiovascular risk from systolic hypertension begins at 115 mm Hg and risk from diastolic hypertension begins at 75 mm Hg. Individuals who are normotensive at 55 years have a 90% likelihood of developing high blood pressure during the next 25 years, and lowering blood pressure toward the new goal level of 120/80 mm Hg will decrease heart attacks, heart failure, stroke, kidney disease, and will save lives.