RT Journal A1 Runhaar J, van der Wouden JC T1 EFfect of oral glucosamine on pain-related disability in patients with chronic low back pain JF JAMA JO JAMA YR 2010 FD October 20 VO 304 IS 15 SP 1673 OP 1673 DO 10.1001/jama.2010.1466 UL http://dx.doi.org/10.1001/jama.2010.1466 AB However, based on the information given in the article, we find it hard to assess the generalizability of the study findings. The authors described that recruitment occurred via general practitioners, physiotherapists, chiropractors, and self-referrals through a newspaper advertisement. It would be helpful to know the distribution of included participants among these 4 methods of recruitment. Self-referred participants had to meet the additional requirement of a recent magnetic resonance imaging (MRI) scan, but it would be helpful to have more information about the Norwegian health care system to understand the implications of this route. A more precise description of the way the investigators recruited the participants would also result in a clearer description of the study population.