RT Journal
A1 Cooper-DeHoff RM, Gong Y, Pepine CJ
T1 HYpertension control and cardiovascular outcomes among patients with diabetes and coronary artery disease—reply
JF JAMA
JO JAMA
YR 2010
FD October 20
VO 304
IS 15
SP 1672
OP 1673
DO 10.1001/jama.2010.1465
UL http://dx.doi.org/10.1001/jama.2010.1465
AB 
In Reply: Drs van Hateren and Bilo inquire about the relationship between age and outcomes in our population of diabetic patients with hypertension and CAD. We recently published another study categorizing all patients from INVEST into 4 groups based on age at baseline (<60, 60-<70, 70-<80 and ≥80 years), and approximately 25% to 30% of patients in each age group had diabetes.1 In that analysis, we observed a progressive increase in risk with increasing age for the primary outcome (first occurrence of all-cause death, nonfatal myocardial infarction, or nonfatal stroke), driven by death, as well as a J-shaped relationship within each age group between the primary outcome and in-treatment systolic and diastolic pressures.1