RT Journal A1 Kuehn BM T1 FDa opioid safety plan promotes patient, physician education to prevent abuse JF JAMA JO JAMA YR 2010 FD August 25 VO 304 IS 8 SP 845 OP 845 DO 10.1001/jama.2010.1200 UL http://dx.doi.org/10.1001/jama.2010.1200 AB In February 2009, the agency first announced it would require the makers of this class of drugs to develop a joint plan to reduce unintentional overdoses involving their products. The announcement was a response to increasing rates of overdose and abuse of opioid pain medications. Data from the Substance Abuse and Mental Health Services Administration's Drug Abuse Warning Network (DAWN) show that emergency department visits involving nonmedical use of prescription opioids increased 111% between 2004 and 2008, with the estimated number of visits rising from 144 644 to 305 885 per year (MMWR Morb Mortal Wkly Rep. 2010;59[23]:705-709).