RT Journal A1 Singh-Manoux A, Stringhini S T1 SOcioeconomic position and mortality—reply JF JAMA JO JAMA YR 2010 FD July 21 VO 304 IS 3 SP 270 OP 271 DO 10.1001/jama.2010.986 UL http://dx.doi.org/10.1001/jama.2010.986 AB The Black Report, commissioned by the Department of Health in the United Kingdom in 1977, was the first comprehensive review of evidence in this domain.1 It identified 4 theoretical explanations for social inequalities: artifactual, natural or social selection, materialist/structural, and cultural/behavioral. Subsequent research has attempted to examine (and promote) the relative importance of one pathway over another, with little consensus.2 In the last decade or so, there has been a surge of interest in neighborhood studies, with increasing recognition of the methodological challenges and the need to identify the causal chain linking exposure to outcome.3 Exposure to environmental toxins and air pollution is likely to contribute to health disparities. Unfortunately, we have no data on air pollution.