RT Journal A1 Stephenson J T1 ALs and neurotoxins JF JAMA JO JAMA YR 2010 FD June 16 VO 303 IS 23 SP 2346 OP 2346 DO 10.1001/jama.2010.798 UL http://dx.doi.org/10.1001/jama.2010.798 AB Previously, researchers proposed that a neurotoxin called β-methylamino-L-alanine (BMAA), produced by cyanobacteria in the roots of certain plants, accumulated in the food chain and caused the very high incidence of an illness similar to amyotrophic lateral sclerosis (ALS) that occurred in the Chamorro people in Guam in the late 1940s and early 1950s. Studies in animals and cultured cells, as well as studies that found BMAA in brain tissue of some patients with Alzheimer disease or ALS, also implicated BMAA as a potential factor in neurodegenerative disease.