RT Journal
A1 Kuehn BM
T1 MEdication helps make therapy work for teens addicted to prescription opioids
JF JAMA
JO JAMA
YR 2010
FD June 16
VO 303
IS 23
SP 2343
OP 2345
DO 10.1001/jama.2010.789
UL http://dx.doi.org/10.1001/jama.2010.789
AB 
Yet medications, such as buprenorphine, can greatly improve patients' adherence to treatment. Garrett, who acknowledged that he was initially skeptical of using prescription drugs to treat patients with these addictions, explained that talk and behavioral therapies can do little to ease the symptoms of withdrawal and strong drug craving that often lead patients to relapse to drug use. But buprenorphine, a partial opioid agonist often paired with naloxone to reduce abuse potential, has been demonstrated in a randomized controlled trial to increase patient retention and improve outcomes (Woody GE et al. JAMA. 2008;300[17]:2003-2011). Now scientists are working to build on this and other emerging evidence to develop therapies targeted to the unique needs of this patient population.