RT Journal A1 Loeb M, Russell M, Earn DD T1 INfluenza vaccination of children and infection rates in the community—reply JF JAMA JO JAMA YR 2010 FD June 16 VO 303 IS 23 SP 2355 OP 2356 DO 10.1001/jama.2010.780 UL http://dx.doi.org/10.1001/jama.2010.780 AB In Reply: Drs Small and Morris hypothesize that the lack of significant differences in serological infection rates between study groups may not have existed had we used LAIV. We agree that this is a possibility, particularly given the number of studies showing indirect benefits with live vaccine.1- 3 We sought to test the effect of inactivated vaccine given its more widespread use and the relative lack of randomized trials evaluating it for indirect benefit.