RT Journal A1 Kuehn BM T1 ALarming nonfatal overdose rates found for opioids, sedatives, and tranquilizers JF JAMA JO JAMA YR 2010 FD May 26 VO 303 IS 20 SP 2020 OP 2021 DO 10.1001/jama.2010.641 UL http://dx.doi.org/10.1001/jama.2010.641 AB Concerns about fatal overdoses involving prescription drugs, particularly opioids, have grown in recent years with the emergence of data suggesting that such deaths are a serious and growing public health problem. As of 2005, unintentional poisoning was second only to motor vehicle crashes as a cause of unintentional death in the United States; among middle-aged persons aged 35 to 54 years, it was the leading cause of unintentional death, according to the US Centers for Disease Control and Prevention.