RT Journal A1 Kuehn BM T1 STudies shed light on risks and trends in pediatric antipsychotic prescribing JF JAMA JO JAMA YR 2010 FD May 19 VO 303 IS 19 SP 1901 OP 1903 DO 10.1001/jama.2010.596 UL http://dx.doi.org/10.1001/jama.2010.596 AB Until recently, only two atypical antipsychotic drugs were approved by the US Food and Drug Administration (FDA) for use in children and adolescents. Risperidone was approved for use in patients aged 13 to 17 years with schizophrenia, patients aged 10 to 17 years for manic or mixed episodes associated with bipolar disorder, and patients aged 5 to 16 years for irritability associated with autism. Aripiprazole was approved to treat schizophrenia in individuals aged 13 to 17 years, and for use alone or as an adjunct to lithium or valproate in individuals aged 10 to 17 years with bipolar mania.