RT Journal A1 Tsai TT, Nallamothu BK, Rumsfeld JS T1 COntraindicated medication use in dialysis patients—reply JF JAMA JO JAMA YR 2010 FD April 21 VO 303 IS 15 SP 1481 OP 1482 DO 10.1001/jama.2010.444 UL http://dx.doi.org/10.1001/jama.2010.444 AB In Reply: We agree with Drs Deal and Hollands that the FDA-directed labeling for enoxaparin dosing in dialysis patients undergoing percutaneous coronary intervention is vague. The FDA revised the content and format of prescription drug labeling in 2006 to make prescribing information clearer and more concise.1 Yet, although eptifibatide and enoxaparin are both predominantly renally cleared and both associated with increased bleeding complications in patients undergoing dialysis, the FDA-directed labeling of the 2 drugs is quite different.