RT Journal A1 Hingorani AD, Psaty BM T1 MOdeling cardiovascular disease prevention—reply JF JAMA JO JAMA YR 2010 FD March 3 VO 303 IS 9 SP 835 OP 835 DO 10.1001/jama.2010.189 UL http://dx.doi.org/10.1001/jama.2010.189 AB Although many of the estimates needed to populate decision models are already available, there has been relatively little comparative work on the performance and cost-effectiveness of available screening tests and risk scores. Also, the preferences of populations that might be targeted for primary prevention have yet to be adequately evaluated. The wide cost differential between generic and proprietary statins also needs to be considered.