RT Journal A1 Leveille SG, Jones RN, Kiely DK, et al T1 CHronic musculoskeletal pain and the occurrence of falls in an older population JF JAMA JO JAMA YR 2009 FD November 25 VO 302 IS 20 SP 2214 OP 2221 DO 10.1001/jama.2009.1738 UL http://dx.doi.org/10.1001/jama.2009.1738 AB Context  Chronic pain is a major contributor to disability in older adults; however, the potential role of chronic pain as a risk factor for falls is poorly understood.Objective  To determine whether chronic musculoskeletal pain is associated with an increased occurrence of falls in a cohort of community-living older adults.Design, Setting, and Participants  The Maintenance of Balance, Independent Living, Intellect, and Zest in the Elderly (MOBILIZE) Boston Study is a population-based longitudinal study of falls involving 749 adults aged 70 years and older. Participants were enrolled from September 2005 through January 2008.Main Outcome Measure  Participants recorded falls on monthly calendar postcards mailed to the study center during an 18-month period.Results  There were 1029 falls reported during the follow-up. A report of 2 or more locations of musculoskeletal pain at baseline was associated with greater occurrence of falls. The age-adjusted rates of falls per person-year were 1.18 (95% confidence interval [CI], 1.13-1.23) for the 300 participants with 2 or more sites of joint pain, 0.90 (95% CI, 0.87-0.92) for the 181 participants with single-site pain, and 0.78 (95% CI, 0.74-0.81) for the 267 participants with no joint pain. Similarly, more severe or disabling pain at baseline was associated with higher fall rates (P < .05). The association persisted after adjusting for multiple confounders and fall risk factors. The greatest risk for falls was observed in persons who had 2 or more pain sites (adjusted rate ratio [RR], 1.53; 95% CI, 1.17-1.99), and those in the highest tertiles of pain severity (adjusted RR, 1.53; 95% CI, 1.12-2.08) and pain interference with activities (adjusted RR, 1.53; 95%CI, 1.15-2.05), compared with their peers with no pain or those in the lowest tertiles of pain scores.Conclusions  Chronic pain measured according to number of locations, severity, or pain interference with daily activities was associated with greater risk of falls in older adults.