RT Journal A1 Kuehn BM T1 SIlent epidemic of viral hepatitis may lead to boom in serious liver disease JF JAMA JO JAMA YR 2009 FD November 11 VO 302 IS 18 SP 1949 OP 1954 DO 10.1001/jama.2009.1588 UL http://dx.doi.org/10.1001/jama.2009.1588 AB Although prevention efforts have helped dramatically reduce the incidence of hepatitis B and C viral infections in the general US population, demographic shifts are leading to growing numbers of chronically infected patients who may develop severe complications such as cirrhosis and hepatic cell carcinoma. A large cohort of individuals infected with hepatitis C virus (HCV) is reaching an age at which liver complications may manifest, and growing numbers of individuals from regions where hepatitis B virus (HBV) infection is endemic are migrating to the United States.