RT Journal
A1 Stephenson J
T1 STrep and ocd, tourette
JF JAMA
JO JAMA
YR 2009
FD October 21
VO 302
IS 15
SP 1640
OP 1640
DO 10.1001/jama.2009.1526
UL http://dx.doi.org/10.1001/jama.2009.1526
AB 
The researchers extracted data on nearly 700 000 patients from a community-based sample of individuals aged between 2 years and 25 years, for a nested case-control study. Among the 129 individuals diagnosed with OCD, 116 diagnosed with TS or tics (108 and 18, respectively), and 4519 controls matched for age, sex, and practice, the researchers identified 20 OCD cases (15.5%) and 13 TS or tic cases (10.3%) exposed to a possible streptococcal infection in the 2 years prior to their diagnosis; similar rates were found among controls. Risk of a prior possible untreated (no antibiotic prescribed) strep infection in the 2 years prior to onset of the disorder was slightly higher in patients with OCD vs controls.