RT Journal A1 Pisarik P T1 COmputed tomographic colonography for detecting advanced neoplasia JF JAMA JO JAMA YR 2009 FD October 14 VO 302 IS 14 SP 1527 OP 1529 DO 10.1001/jama.2009.1435 UL http://dx.doi.org/10.1001/jama.2009.1435 AB Assume that one 10-year cycle would require 2 CT colonography screenings vs 1 optical colonoscopy, 20% of CT colonography-screened patients need an optical colonoscopy after CT colonography for each 5-year cycle, and 1 half-day of work would be lost for CT colonography and 1 day lost for optical colonoscopy. In that case, total time off work would be 1.4 days for those screened with CT colonography vs 1 day with colonoscopy; those screened by CT colonography would experience 2.4 colon cleansing procedures vs 1 for optical colonoscopy. It seems unlikely that patients would adhere better to CT colonography screening. Prospective studies are required to answer this question.