RT Journal
A1 Gharavi A, Diamond JA, Phillips RA
T1 EXercise capacity and left ventricular function
JF JAMA
JO JAMA
YR 2009
FD June 10
VO 301
IS 22
SP 2325
OP 2327
DO 10.1001/jama.2009.697
UL http://dx.doi.org/10.1001/jama.2009.697
AB 
Although left ventricular diastolic function may be independent of, or precede, left ventricular hypertrophy in patients with stage 1 or treated hypertension,2- 3 we have previously demonstrated that both left ventricular mass and diastolic function are related to exercise capacity in patients with newly diagnosed or uncontrolled hypertension of stage 2 or greater.4 Because in the study by Grewal et al the impaired diastolic function group had a higher prevalence of hypertension, increased left ventricular mass could be a major confounder mediating the relationship between exercise performance and diastolic function. In addition, because of the strong relationship between left ventricular mass and cardiovascular morbidity and mortality,5 we believe that it is important for the authors to explore the relationship between exercise capacity and left ventricular mass in their population.