RT Journal
A1 Kickler T
T1 Dr william w. duke: Pioneer in platelet research
JF JAMA
JO JAMA
YR 2009
FD June 3
VO 301
IS 21
SP 2267
OP 2269
DO 10.1001/jama.2009.787
UL http://dx.doi.org/10.1001/jama.2009.787
AB 
In 1910, when Duke1 published an article in JAMA on the role of platelets in hemostasis, probably few individuals realized that this report would be judged as one of the outstanding contributions to the science of medicine during the first half of the 20th century.2 The application of a simple, low-tech approach to answering the elusive role of platelets in hemostasis provided the foundation for many subsequent developments in platelet biology and therapy. This Commentary will focus on Duke's observations and on how his observations have led to improved understanding of the pathophysiology, diagnosis, and treatment of platelet-related disorders.